Levothyroxine Therapy Adequacy, Dose Estimation and Vitamin D Effect Assessment in a Sample of Iraqi Female Patients with Different Causes of Hypothyroidism

Authors

  • Ban A. Al-Shimmran Author
  • Zinah M. Anwer
  • Bassam H. Al-Jarrah

DOI:

https://doi.org/10.31351/vol29iss2pp245-252

Keywords:

Hypothyroidism, Levothyroxine, Thyroidectomy, Vitamin D

Abstract

Exogenous levothyroxine dose modulation and euthyroidism achievement is a persistent challenge in clinical settings. This study strives to assess the adequacy of treatment and identify the patients’ factors that can be used to estimate the euthyroid levothyroxine dose. A secondary objective was to assess vitamin D supplementation impact on thyroid status.

A review of a prospectively collected information from 142 female patients from Baghdad Center of Nuclear Medicine from June 2019 until March 2020 who were receiving levothyroxine for different causes was done. After a follow-up period, the patients’ thyroid tests were assessed and the euthyroid doses for each cause category were statistically analyzed. Thyroid function was assessed before and after three months of vitamin D supplementation for 29 out of 50 patients who measured its level.

Sixty-six patients (47%) of the sample were inadequately replaced

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Published

2020-12-30

How to Cite

1.
Al-Shimmran BA, M. Anwer Z, H. Al-Jarrah B. Levothyroxine Therapy Adequacy, Dose Estimation and Vitamin D Effect Assessment in a Sample of Iraqi Female Patients with Different Causes of Hypothyroidism. Iraqi Journal of Pharmaceutical Sciences [Internet]. 2020 Dec. 30 [cited 2024 Nov. 5];29(2):245-52. Available from: https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/1141