Carvone exerts lung anti-inflammatory effect through hampering NF-KB pathway in lipopolysaccharide-induced acute lung injury in mice

Authors

  • Samah Mahde Department of Pharmacology and Toxicology, College of Pharmacy, University of Baghdad
  • Sarmad Haishm Department of Pharmacology and Toxicology, College of Pharmacy, University of Baghdad

DOI:

https://doi.org/10.31351/vol32iss1pp125-132

Abstract

                Background: Acute lung injury (ALI) is among the most serious conditions characterized by an exacerbation of inflammatory response that can result from a persistent lung infection. Carvone is chiral monoterpenoid ketone present in the essential oils of dill, caraway, and spearmint. It shows antioxidant, anti-inflammatory, and antimicrobial effects among others. In this study, the lung anti-inflammatory and protective effects and potential mechanism of action of carvone were investigated in ALI induced by Lipopolysaccharide (LPS).

References

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Published

2023-06-16