Pharmacological and Anticancer Potential of Black Ginger (Kaempferia parviflora) - Review Article

Abstract

Kaempferia parviflora (KP), also known as Black ginger or Kra-chi-dum in Thailand, is a Zingiberaceae plant native to Thailand and Malaysia. This plant is commonly used by the community as a spice in cooking and healthy drinks for disease prevention and treatment. According to research, KP extracts have broad bioactivity against infectious diseases caused by viruses and bacteria, as well as diseases related to metabolic disorders such as obesity, diabetes, aging, and gastrointestinal disorders. KP is also effective as an anticancer agent. This review article focuses on KP's anticancer activity and possible mechanisms of action. Furthermore, the botanical aspect and content of active compounds are investigated in this article. Considering KP's high potential as a medicinal plant, the potential interactions of KP with synthetic drugs and its potential formulation are investigated. According to the findings of this review, KP has anticancer and antimetastatic activity, and the active ingredient responsible for this activity is methoxyflavone.