Assessment of Certain Hematological Indices and Interlukin-6 in Workers and Individuals Who Live Near to Crude Oil Wells in Middle Petroleum

Authors

  • Mariam.R. Alghara
  • Ausama Ayob Jaccob College of Pharmacy, Basra University
  • Azza.Sajid. Jabbar

DOI:

https://doi.org/10.31351/vol32iss1pp237-244

Abstract

Environmental exposures to a variety of pollutant elements especially fuel waste products may result in harmful impacts on several physiological systems. The inflammatory response and the hematological system are the major affected systems. The aim of the study is to reveal the impact of oil exposure on several hematological parameters and IL-6 of oil workers and to detect which parameters are more affected as prognosticators for clinical disorders. This study included three groups, 50 persons in each. Control group; Group1 workers at oil wells; and Group2 who live close to oil wells. Physical parameters, serum interleukin 6 , random blood glucose , hematological parameters are measured. Significant rise in pulse rate, serum interleukin 6 and RBG were documented in workers. Hematological parameters were adversely affected by air pollution . We found a significant rise in platelet count in Group 1 patients . The correlation between IL-6 and certain hematological indices revealed that each of WBC and platelets were significantly correlated to IL-6. In conclusion People work or lived close to oil wells area showed alterations in hematological and inflammatory parameters may be related to continuous exposure to petrol fumes, which also results in a considerable increase in interleukin-6.

Keyword:Oil wells, hematological indices, interleukin 6.

How to Cite

1.
Mariam.R. Alghara, Jaccob AA, Azza.Sajid. Jabbar. Assessment of Certain Hematological Indices and Interlukin-6 in Workers and Individuals Who Live Near to Crude Oil Wells in Middle Petroleum . Iraqi Journal of Pharmaceutical Sciences [Internet]. 2023 Jun. 27 [cited 2024 Dec. 24];32(1):237-44. Available from: https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/1866

Publication Dates

References

Al-dabbas MA, Ali LA, Afaj AH. The effect of Kirkuk Oil Refinery on Air pollution of Kirkuk City-Iraq. Iraqi J Sci. 2012;17–8.

Kadhem JA, Reza KS, Ahmed WK. Alternative Fuel Use in Iraq: A way to Reduce Air Pollution. Eur J Eng Res Sci. 2017;2(5):20.

Kampa M, Castanas E. Human health effects of air pollution. Environ Pollut. 2008;151(2):362–7.

Gigantesco A, Giuliani and M. Quality of life in mental health services with a focus on psychiatric rehabilitation practice. Ann Ist Super Sanità. 2011;47(4):363–72.

Al-Darraji AH. Endocrine disorders in fuel stations workers. APJMT 10;1.

Sajid Jabbar A, Ali ET. Impact of Petroleum Exposure on Some Hematological Indices, Interleukin-6, and Inflammatory Markers of Workers at Petroleum Stations in Basra City. J Environ Public Health. 2020;2020.

Rezazadeh Azari M, Naghavi Konjin Z, Zayeri F, Salehpour S, Seyedi MD. Occupational exposure of petroleum depot workers to BTEX compounds. Int J Occup Environ Med. 2012;3(1):39–44.

Gillis B, Gavin IM, Arbieva Z, King ST, Jayaraman S, Prabhakar BS. Identification of human cell responses to benzene and benzene metabolites. Genomics. 2007;90(3):324–33.

Abdel Rasoul G, Salem E, Allam H, Shehata Y, Abu-Salem M, El-Sayed Zagloul A. Neurobehavioral and hematological health disorders among fuel supply station workers. Menoufia Med J. 2017;30(4):1103.

Ali ET, Jabbar AS, Mohammed AN. A Comparative Study of Interleukin 6, Inflammatory Markers, Ferritin, and Hematological Profile in Rheumatoid Arthritis Patients with Anemia of Chronic Disease and Iron Deficiency Anemia. Anemia. 2019;2019.

Wojciech gj and W. health risk in road transport workers part i . occupational exposure to chemicals , biomarkers of effect. 2020;32(3):0–14.

Smith MT, Jones RM, Smith AH. Benzene exposure and risk of non-Hodgkin lymphoma. Cancer Epidemiol Biomarkers Prev. 2007;16(3):385–91.

Glass DC, Gray CN, Jolley DJ, Gibbons C, Sim MR, Fritschi L, et al. Leukemia risk associated with low-level benzene exposure. Epidemiology. 2003;14(5):569–77.

Rashid MHU, Chowdhury MRK, Huq ME, Rahman S, Mondal NT. A Study on Highly Sensitive C-Reactive Protein (Hs-CRP) in Patients with Bronchial Asthma. Delta Med Coll J. 2018;6(2):62–7.

Verma DK, Des Tombe K. Benzene in gasoline and crude oil: Occupational and environmental implications. Am Ind Hyg Assoc J. 2002;63(2):225–30.

Lee I, Park H, Kim MJ, Kim S, Choi S, Park J, et al. Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds is associated with a risk of obesity and diabetes mellitus among Korean adults: Korean National Environmental Health Survey (KoNEHS) 2015–2017. Int J Hyg Environ Health. 2022;240:113886.

Wiwanitkit V. Benzene exposure and hypertension: An observation. Cardiovasc J South Africa. 2007;18(4):264–5.

Chuang KJ, Chen HW, Liu IJ, Chuang HC, Lin LY. The effect of essential oil on heart rate and blood pressure among solus por aqua workers. Eur J Prev Cardiol. 2014;21(7):823–8.

Künzli N, Tager IB. Air pollution: From lung to heart. Swiss Med Wkly. 2005;135(47–48):697–702.

Al-Helaly LA, Ahmed TY. Antioxidants and Some Biochemical Parameters in Workers Exposed to Petroleum Station Pollutants in Mosul City, Iraq. Vol. 3, Int. Res. J. Environment Sci. International Science Congress Association. 2014.

Augusto N, Filho R, Urrutia-pereira M, Amato GD, Cecchi L. Air pollution and indoor settings. World Allergy Organ J. 2021;14(1):100499.

Zhang B, Liu L, Guo L, Guo S, Zhao X, Liu G, et al. Telomere length mediates the association between polycyclic aromatic hydrocarbons exposure and abnormal glucose level among Chinese coke oven plant workers. Chemosphere. 2021;266:129111.

De Coster S, Van Larebeke N. Endocrine-disrupting chemicals: Associated disorders and mechanisms of action. J Environ Public Health. 2012;2012.

Downloads

Published

2023-06-27